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Project C04: Goal pursuit despite emotional distraction: Neural network mechanisms of emotional interference inhibition and their role for resilience

Principal Investigators

Prof. Dr. Oliver Tüscher

Vice-Chair and Attending, Department of Psychiatry and Psychotherapy

Group leader; Head of Clinical Investigation Center (CIC) at LIR; 


Prof. Dr. Michael Wibral

Professor für Datengetriebene Analyse biologischer Netzwerke

Project Team

Our Research

Using EEG, C04 will identify neural markers of emotional stimulus interference inhibition, focusing on beta band oscillatory activity. It will be tested whether these markers generalize across to-be-protected goal-directed cognitive functions and whether they are associated with resilience - in subjects provided by Z03. By simultaneous EEG/MEG, C04 will elucidate the neural basis of these markers to understand their network-level mechanisms, specifically in relation to the dynamics of information transfer.

Publications

Novelli L, Wollstadt P, Mediano P, Wibral M, Lizier JT (2019) Large-scale directed network inference with multivariate transfer entropy and hierarchical statistical testing. Netw Neurosci 3(3):827−847.

>> Link to PubMed

Sebastian A, Rössler K, Wibral M, Mobascher A, Lieb K, Jung P, Tüscher O (2017) Neural architecture of selective stopping strategies: distinct  brain activity patterns are associated with attentional capture but not  with outright stopping. J Neurosci 37(40):9785-9794.

>> Link to PubMed

Kalisch R, Baker DG, Basten U, Boks MP, Bonanno GA, Brummelman E, Chmitorz A, Fernàndez G, Fiebach CJ, Galatzer-Levy I, Geuze E, Groppa S, Helmreich I, Hendler T, Hermans EJ, Jovanovic T, Kubiak T, Lieb K, Lutz B, Müller MB, Murray RJ, Nievergelt CM, Reif A, Roelofs K, Rutten BPF, Sander D, Schick A, Tüscher O, Van Diest I, van Harmelen A-L, Veer IM, Vermetten E, Vinkers CH, Wager TD, Walter H, Wessa M, Wibral M, Kleim B (2017) The resilience framework as a strategy to combat stress-related disorders. Nat Hum Behav 1:784-90.

>> Link to PubMed