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Project C04: Goal pursuit despite emotional distraction: Neural network mechanisms of emotional interference inhibition and their role for resilience

Principal Investigators

Prof. Dr. Oliver Tüscher

Group leader; Director, FTN/DRZ - Clinical Investigation Center (CIC); Vice-Chair and Attending, Dept. of Psychiatry and Psychotherapy

Prof. Dr. Michael Wibral

Professor (W2)

Project Team

Dr. Yuranny Cabral-Calderin, Postdoc
Anya Dietrich, PhD student
Dr. Johann-Philipp Horstmann, Assistant physician
Svenja Hummel, MD student
Dr. Bianca Kollmann, Postdoc
Eduardo Pinzuti, PhD student
Michael Schaum, PhD student
Dr. Alexandra Sebastian, Postdoc
Dr. Dr. Daniel Turner, Postdoc

Our Research

Using EEG, C04 will identify neural markers of emotional stimulus interference inhibition, focusing on beta band oscillatory activity. It will be tested whether these markers generalize across to-be-protected goal-directed cognitive functions and whether they are associated with resilience - in subjects provided by Z03. By simultaneous EEG/MEG, C04 will elucidate the neural basis of these markers to understand their network-level mechanisms, specifically in relation to the dynamics of information transfer.

Publications

Sebastian A, Rössler K, Wibral M, Mobascher A, Lieb K, Jung P, Tüscher O (2017) Neural Architecture of Selective Stopping Strategies: Distinct Brain Activity Patterns Are Associated with Attentional Capture But Not with Outright Stopping. J Neurosci 2017 37(40):9785-9794.

>> Link to PubMed

Kalisch R, Baker DG, Basten U, Boks MP, Bonanno GA, Brummelman E, Chmitorz A, Fernàndez G, Fiebach CJ, Galatzer-Levy I, Geuze E, Groppa S, Helmreich I, Hendler T, Hermans EJ, Jovanovic T, Kubiak T, Lieb K, Lutz B, Müller MB, Murray RJ, Nievergelt CM, Reif A, Roelofs K, Rutten BPF, Sander D, Schick A, Tüscher O, Van Diest I, van Harmelen A-L, Veer IM, Vermetten E, Vinkers CH, Wager TD, Walter H, Wessa M, Wibral M, Kleim B (2017) The resilience framework as a strategy to combat stress-related disorders. Nat Hum Behav 1:784-90.

>> Link to PubMed