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Dr.
Jennifer Winter

Group leader

Contact

Institute of Human Genetics
University Medical Center
Johannes Gutenberg University Mainz
Obere Zahlbacher Str. 63
55131 Mainz

+49 (0) 6131 17 9684

CRC 1193 PROJECTS

Expertise

Neurogenetics, Posttranscriptional gene regulation

Molecular mechanisms underlying autism spectrum disorders, RNA-mediated regulation of gene expression during development and disease, microRNAs and RNA-binding proteins in neurodevelopment

Vita

Since 2017

Head of the molecular-genetic diagnostics lab, Institute of Human Genetics, University Medical Center, Mainz, Germany

Since 2012

Junior research group leader, Institute of Human Genetics, University Medical Centre, Mainz, Germany

2008 – 2012

Project group leader, Max Planck Institute of Immunobiology and Epigenetics, department Molecular Embryology, Freiburg, Germany

2003 – 2008

Postdoctoral fellow, Max Planck Institute of Molecular Genetics, Berlin (Department Ropers)

Publications

Menzel L, Kleber L, Friedrich C, Hummel R, Dangel L, Winter J, Schmitz K, Tegeder I, Schäfer MK (2017) Progranulin protects against exaggerated axonal injury and astrogliosis following traumatic brain injury. Glia 65(2):278-292

>> Link to PubMed

Wenzel M, Schüle M, Casanovas S, Strand D, Strand S, Winter J (2016) Identification of a classic nuclear localization signal at the N terminus that regulates the subcellular localization of Rbfox2 isoforms during differentiation of NMuMG and P19 cells. FEBS Lett 590(24):4453-4460.

>> Link to PubMed

Bräutigam C, Rago L, Rolke A, Waldmeier L, Christofori G, Winter J (2014) The RNA-binding protein Rbfox2: an essential regulator of EMT-driven alternative splicing and a mediator of cellular invasion. Oncogene 33(9):1082-92.

>> Link to PubMed

Rago L, Beattie R, Taylor V, Winter J (2014) miR379-410 cluster miRNAs regulate neurogenesis and neuronal migration by fine-tuning N-cadherin. EMBO J 33(8):906-20.

>> Link to PubMed

Bräutigam C, Raggioli A, Winter J (2013) The Wnt/β-catenin pathway regulates the expression of the miR-302 cluster in mouse ESCs and P19 cells. PLoS One 8(9):e75315.

>> Link to PubMed

Awards, Grants and Honor

2003 - 2005

Postdoctoral stipend, Max Planck Institute for Molecular Genetics, Berlin, Germany