EN DE

PD Dr.
Johannes Vogt

Principal Investigator

Contact

Institute for Microanatomy and Neurobiology
University Medicine Mainz

Langenbeckstr. 1
55131 Mainz

+49 (0) 6131 17 8091

CRC 1193 PROJECTS

Expertise

Neuroanatomy, Cell Biology, Electrophysiology

Role of bioactive lipids in cortical information processing and psychiatric disorders

Role of bioactive lipids in the development and maintenance of neuronal circuits

Vita

01/2017

Habilitation, Dr. habil degree

Since 2010

Group leader (PI), University Medical Center Mainz, Institute of Microanatomy and Neurobiology

2004 – 2010

Group leader, Charité University Medicine, Institute of Cell Biology and Neurobiology, Berlin, Germany

2003 – 2004

Marie-Curie scholarship, University of Maastricht, Dept. for Psychiatry and Neuropsychology, the Netherlands

2004

Postdoctoral Stipend of the DFG in the Research Training Group GRK 238

2003

Postdoctoral Fellow Charité University Medicine, Institute for Neuroimmunology, Berlin, Germany

2001 – 2003

Predoctoral Fellow in the group of Prof. Dr. Bernd Heimrich, Charité University Medicine, Institute of Cell Biology and Neurobiology, Berlin, Germany

2000 – 2001

Medical Doctor, Charité University Medicine, Clinic for Neurology, Berlin, Germany

Publications

Vogt J, Kirischuk S, Unichenko P, Schlüter L, Pelosi A, Cheng J, Yang JW, Strauss U, Prokudin A, Bharati BS, Aoki J, Chun J, Lutz B, Luhmann HJ, Nitsch R (2017) Synaptic phospholipid signaling modulates synchronized cortical activity during brain development altering adult connectivity and memory. Cereb Cortex 27(1):131-145.

>> Link to PubMed

Cheng J, Sahani S, Hausrat TJ, Yang JW, Endle H, Liu X, Li Y, Böttche R, Radyushkin K, Hoerder-Suabedissen A, Molnár Z, Prouvot PH, Trimbuch T, Ninnemann O, Fan W, Visentin B, Sabbadini R,  Stroh A, Luhmann HJ, Kneussel M, Nitsch R, Vogt J (2016) Precise somatotopic thalamocortical axon guidance depends on LPA-mediated PRG-2/Radixin signaling. Neuron 92(1):126-142.

>> Link to PubMed

Liu X, Huai J, Endle H, Schlüter L, Fan, W, Li Y, Richers S, Yurugi H, Rajalingam K, Ji H, Cheng H, Rister B, Horta G, Baumgart J, Berger H, Laube G, Schmitt U, Schmeisser MJ, Boeckers TM, Deller T, Vlachos A, Tenzer S, Nitsch R, Vogt J (2016) PRG-1 regulates spine density via PP2A/ß1-integrin signaling. Developmental Cell 8;38(3):275-90.

>> Link to PubMed

Vogt J, Yang JW, Mobascher A, Cheng J, Li Y, Liu X, Baumgart J, Thalman C, Kirischuk S, Unichenko P, Horta G, Radyushkin K, Stroh A, Richers S, Sahragard N, Distler U, Tenzer S, Qiao L, Lieb K, Tüscher O, Binder H, Ferreiros N, Tegeder I, Morris AJ, Groppa S, Nürnberg P, Toliat MR, Winterer G, Luhmann HJ, Huai J, Nitsch R (2016) Molecular cause and functional impact of altered synaptic lipid signaling due to a prg-1 gene SNP. EMBO Mol Med 8, 25-38.

>> Link to PubMed

Trimbuch T*, Beed P*, Vogt J*, Schuchmann S, Maier N, Kintscher M, Breustedt J, Schuelke M, Streu N, Kieselmann O, Brunk I, Laube G, Strauss U, Battefeld A, Wende H, Birchmeier C, Wiese S, Sendtner M, Kawabe H, Kishimoto-Suga M, Brose N, Baumgart J, Geist B, Aoki J, Savaskan NE, Bräuer AU, Chun J, Ninnemann O, Schmitz D, Nitsch R (2009) Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling. Cell 18; 138(6): 1222-35. *equal contributing

>> Link to PubMed

Awards, Grants and Honor

2003 – 2004

Marie-Curie Scholarship, University of Maastricht, the Netherlands

2003

Postdoctoral Stipend of the DFG in the Research Training Group GRK 238, Charité University Medicine Berlin, Germany

Memberships

Since 2000

Member of the “Neurowissenschaftliche Gesellschaft”