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Prof. Dr.
Albrecht Stroh

Head of Research Group “Molecular Imaging and Optogenetics” at the Institute of Pathophysiology

Head of the “Mainz Animal Imaging Center (MAIC)” and Group Leader at LIR


Contact

Research Group Molecular Imaging and Optogenetics
Focus Program Translational Neurosciences (FTN) &
Institute of Microscopic Anatomy and Neurobiology
University Medical Center of the Johannes Gutenberg-University Mainz
&
Leibniz Institute for Resilience Research (LIR) gGmbH

Hanns-Dieter-Hüsch-Weg 19
55128 Mainz

+49 (0) 6131 39 21347

CRC 1193 PROJECTS

Expertise

Neuroimaging, Optogenetics

Thalamo-cortical oscillations, adult neurogenesis, development of simultaneous optical imaging and optogenetic manipulation methods, 2-Photon-Calcum imaging of cortical microcircuits, optogenetic-fMRI of thalamocortical circuits

Vita

Since 01/2020

Research Group Leader at Leibniz Institute for Resilience Research (LIR) gGmbH, Mainz

01/2018 – 12/2019

Research Group Leader at German Resilience Center (DRZ) gGmbH, Mainz

Since 01/2018

Tenured Associate Professor (W2) of Molecular Imaging and Optogenetics, Univ. Medical Center of JGU Mainz

Since 04/2012

W1 professor, Head of Mainz Animal Imaging Center (MAIC), Mainz

2007 – 2012

Research Assistant at the Institute of Neuroscience, teaching at M.D./Ph.D. Program, Technical University Munich, with Arthur Konnerth

2005 – 2007

Postdoctoral Scholar at the Dept. of Bioengineering, Stanford University, with Karl Deisseroth

Publications

Meyer B, Mann C, Götz M, Gerlicher A, Saase V, Yuen KSL, Aedo-Jury F, Gonzalez-Escamilla G, Stroh A, Kalisch R (2019) Increased neural activity in mesostriatal regions after prefrontal transcranial direct current stimulation and L-DOPA administration. J Neurosci 39(27):5326–5335. doi: 10.1523/JNEUROSCI.3128-18.2019

>> Link to PubMed

Ellwardt E, Pramanik G, Luchtman D, Novkovic T, Jubal ER, Vogt J, Arnoux I, Vogelaar CF, Mandal S, Schmalz M, Barger Z, Ruiz de Azua I, Kuhlmann T, Lutz B, Mittmann T, Bittner S, Zipp F, Stroh A (2018) Maladaptive cortical hyperactivity upon recovery from experimental autoimmune encephalomyelitis. Nat Neurosci 21(10):1392−1403.

>> Link to PubMed

Schmid F, Wachsmuth L, Schwalm M, Prouvot P-H, Jubal E R, Fois C, Pramanik, Zimmer C, Faber C, Stroh A (2016) Assessing sensory versus optogenetic network activation by combining (o)fMRI with optical Ca2+ recordings. J Cereb Blood Flow Metab 36(11):1885-1900.

>> Link to PubMed

Groh A, Bokor H, Mease RA, Plattner VM, Hangya B, Stroh A, Deschenes M, Acsády L (2014) Convergence of Cortical and Sensory Driver Inputs on Single Thalamocortical Cells. Cereb Cortex 24:3167-79.

>> Link to PubMed

Stroh A, Adelsberger H, Groh A, Rühlmann C, Fischer S, Schierloh A, Deisseroth K, Konnerth A (2013) Making waves: initiation and propagation of corticothalamic Ca2+ waves in vivo. Neuron 77:1136-50.

>> Link to PubMed

Stroh A, Tsai HC, Wang LP, Zhang F, Kressel J, Aravanis A, Santhanam N, Deisseroth K, Konnerth A, Schneider MB (2011) Tracking stem cell differentiation in the setting of automated optogenetic stimulation. Stem Cells 29:78-88.

>> Link to PubMed

Stroh A, Faber C, Neuberger Th, Lorenz P, Sieland K, Jakob P, Webb A, Pilgrimm H, Schober R, Pohl E, Zimmer C (2005) In vivo detection limits of magnetically labeled embryonic stem cells in the rat brain using high-field (17.6 T) magnetic resonance imaging. Neuroimage 24:635-45.

>> Link to PubMed

Coordinating Functions

2014

Initiator of a workshop within the „Lectures on MR“ series of the European Society for Magnetic ResonanceResonance in Medicine and Biology (ESMRMB): “fMRI and optogenetics: Probing networks in the animal brain“ at Münster University Hospital

Editorial and Scientific Advisory Board

2018

Editor of a volume on Optogenetics within the “Neuromethods” series of Springer, New York

Awards, Grants and Honor

2015

Funding for 9.4 T small animal MRI, DFG Major Research Instrumentation Programme

2015

Positive evaluation of W1-Professorship at Johannes Gutenberg-University Mainz

2013

Funding for 2 two-photon microscopes with optogenetics integration, DFG Major Research Instrumentation Programme

2009

Certificate of Merit for contribution: “Rat fMRI at 17.6 T upon implantation of an optical fiber”, ESMRMB 2009

2005

Kurt-Decker-Award, Annual national award for exceptional research assigned by the German Society for Neuroradiology (DGNR)

2003

Young Investigators Award for exceptional research in life sciences and medicine assigned by the Roland-Ernst-Foundation, Leipzig, German

Memberships

Society for Neuroscience, German Neuroscience Society, International Society for Magnetic Resonance in Medicine