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Prof. Dr.
Benedikt Berninger

Professor

Contact

Institute of Physiological Chemistry
University Medical Center
Johannes Gutenberg University Mainz
Hanns-Dieter-Hüsch-Weg 19
55128 Mainz

+49 (0) 6131 39 21334

CRC 1193 PROJECTS

Expertise

Adult neurogenesis, neural stem cell lineage progression, cerebral organoids, direct lineage reprogramming, functional integration of new neurons into pre-existing networks

Vita

Since 10/2012

Professor for Physiological Chemistry (W2), Johannes Gutenberg University Medical Center Mainz

08/2011 – 05/2012

Akademischer Oberrat, Institute of Physiology, Physiological Genomics, Ludwig Maximilians University Munich

08/2005 – 07/2011

Akademischer Rat, Institute of Physiology, Physiological Genomics, Ludwig Maximilians University Munich

06/2003 – 07/2005

Research Assistant at the Institute of Stem Cell Research, Helmholtz Zentrum, München

03/2001 - 05/2003

Research Assistant at the Max Planck Institute of Neurobiology, Martinsried/Munich

12/2000 – 02/2001

Postdoctoral researcher and Human Frontier Science Program Organization Short-term Fellow (supervisor: J. Frisén) Medical Nobel Institute, Karolinska Institute, Stockholm, Sweden

10/1996 – 11/2000

Postdoctoral researcher and Human Frontier Science Program Organization Long-term Fellow (supervisor: M.-m. Poo), Department of Biology, University of California San Diego, CA, USA

01/1993 – 07/1996

Doctoral student (supervisor: H. Thoenen), Department of Neurochemistry, Max Planck Institute for Psychiatry, Martinsried/Munich

Publications

Bergami M, Masserdotti G, Temprana SG, Motori E, Eriksson T, Göbel J, Yang SM, Conzelmann KK, Schinder AF, Götz M, Berninger B (2015) A critical period of experience-dependent remodelling of adult-born neuron connectivity. Neuron 85:710-7.

>> Link to PubMed

Heinrich C, Spagnoli FM, Berninger B (2015) In vivo reprogramming for tissue repair. Nat Cell Biol 17:204-11.

>> Link to PubMed

Ortega F, Gascón S, Masserdotti G, Deshpande A, Simon S, Fischer J, Dimou L, Lie DC, Schroeder T, Berninger B (2013) Oligodendrogliogenic and neurogenic adult subependymal zone neural stem cells constitute distinct lineages and exhibit differential responsiveness to Wnt signaling. Nat Cell Biol 15:602-13.

>> Link to PubMed

Karow M, Sánchez R, Schichor C, Masserdotti G, Ortega F, Heinrich C, Gascón S, Khan MA, Lie DC, Dellavalle A, Cossu G, Goldbrunner R, Götz M*, Berninger B* (2012) Reprogramming of pericyte-derived cells of the adult human brain into induced neuronal cells. Cell Stem Cell 11:471-76. *equal contribution

>> Link to PubMed

Costa MR, Ortega F, Brill MS, Beckervordersandforth R, Petrone C, Schroeder T, Götz M, Berninger B (2011) Continuous live imaging of adult neural stem cell division and lineage progression. Development 138:1057-68.

>> Link to PubMed

Editorial and Scientific Advisory Board

2013

Associate Editor of Neurogenesis (Editor-in-Chief Verdon Taylor)

2012

Review Editor Frontiers in Neurodegeneration

2011

Faculty of 1000, Neurodevelopmental Section

2010

 Review Editor Frontiers in Neurogenesis

Awards, Grants and Honor

2017

Wellcome Trust Investigator Award in Science

2000

Short-term Fellowship of the Human Frontier Science Program Organization

1996

Long-term Fellowship of the Human Frontier Science Program Organization