Torfi Sigurdsson, Ph.D.

Independent Group Leader


Institute for Neurophysiology
Neuroscience Center
Goethe University Frankfurt/Main
Theodor-Stern-Kai 7
60596 Frankfurt/Main

+49 (0) 69 6301 84098



In vivo Electrophysiology

Learning and memory, sensory processing, fear and anxiety, psychiatric disease models, neural synchrony, electrophysiology, optogenetics


Since 07/2013

Faculty, International Max Planck Research School for Neural Circuits, Frankfurt

Since 09/2011

Independent Group Leader, Institute of Neurophysiology, Goethe University Frankfurt

03/2007 – 9/2011

Postdoctoral Research Scientist, Columbia University

03/2006 – 9/2007

Postdoctoral Research Scientist, New York University

09/1999 – 05/2006

Doctoral student, New York University


Babl S, Rummell B, Sigurdsson T (2019) The spatial extent of optogenetic silencing in transgenic mice expressing channelrhodopsin in inhibitory interneurons. Cell Reports 29(5):1381–1394.e4.

>> Link to PubMed

Duvarci S, Simpson EH, Schneider G, Kandel ER, Roeper J, Sigurdsson T (2018) Impaired recruitment of dopamine neurons during working memory in a mouse model of striatal D2 receptor overexpression. Nat Commun 9:2822. doi: 10.1038/s41467-018-05214-4

>> Link to PubMed

Rummell BP, Klee JL, Sigurdsson T (2016) Attenuation of Responses to Self-Generated Sounds in Auditory Cortical Neurons. J Neurosci 36(47):12010-12026.

>> Link to PubMed

Sigurdsson T (2016) Neural circuit dysfunction in schizophrenia: Insights from animal models. Neurosci 321:42-65.

>> Link to PubMed

O'Neill PK, Gordon JA, Sigurdsson T (2013) Theta Oscillations in the Medial Prefrontal Cortex Are Modulated by Spatial Working Memory and Synchronize with the Hippocampus through Its Ventral Subregion. J Neurosci 33:14211-24.

>> Link to PubMed

Sigurdsson T, Stark KL, Karayiorgou M, Gogos JA, Gordon JA (2010) Impaired Hippocampal-Prefrontal Synchrony in a Genetic Mouse Model of Schizophrenia. Nature 464:763-7.

>> Link to PubMed

Sigurdsson T, Doyere V, Cain CK, LeDoux JE (2007) Long-term potentiation in the amygdala: a cellular mechanism of fear learning and memory. Neuropharmacol 52:215-27.

>> Link to PubMed

Editorial and Scientific Advisory Board

Ad hoc reviewer for Neuroscience, Frontiers in Behavioral Neuroscience, Psychoneuroendrinology, British Journal of Pharmacology, Cerebral Cortex

Awards, Grants and Honor

2019 – 2022

DFG Research Grant (SI 1942/2-2)

2017 – 2020

DFG Research Grant within Priority Program 1665 (SI 1942/4-1)

2014 – 2017

ANR-DFG Research Grant (SI 1942/3-1)

2014 – 2017

Member of BMBF Juniorverbund in Systemmedizin (‘PsyChoSys’)

2013 – 2016

DFG Research Grant (SI 1942/1-1)

2013 – 2016

DFG Research Grant within Priority Program 1665 (SI 1942/2-1)

2011 – 2013

NARSAD Young Investigator Award

2010 – 2011

Sackler Institute Award

1999 – 2000

American-Scandinavian Foundation, Thor Thors Memorial Scholarship