Prof. Dr.
Sergiu Groppa

Professor, Chair of Section of Movement Disorders and Neurostimulation, Consultant of the Clinic of Neurology


Clinic of Neurology
Section of Movement Disorders and Neurostimulation
Clinic of Neurology & Focus Program Translational Neurosciences (FTN)
University Medical Center Johannes Gutenberg-University Mainz
Langenbeckstr. 1
55131 Mainz

+49 (0) 6131 17 2998



Neurostimulation, EEG

Cortico-cortical networks, structural and functional brain mapping, invasive and non-invasive brain stimulation, movement disorders


Since 11/2014

W2-Professor of Neurology and Movement Disorders, Clinic of Neurology, Johannes Gutenberg University Mainz

2007 – 2014

Research assistant, Department of Neurology, University Hospital Kiel

2007 – 2009

Postdoctoral Fellow, “Laboratory of Neurostimulation and Neuroimaging", Clinic of Neurology, University Hospital Kiel (Hartwig Siebner)

2007 – 2009

Postdoctoral Fellow in the SFB 654 "Plasticity and Sleep", subproject A06, "Neocortical processing modes of the sleeping brain as a neural substrate for memory consolidation in humans", Jan Born, Lisa Marshall

2004 – 2008

MD-Thesis: ''Excitability of the motor cortex in subjects with and without photosensitive diopathic generalized epilepsy'', Department of Pediatric Neurology, University Hospital Kiel


Muthuraman M, Deuschl G, Koirala N, Riedel C, Volkmann J, Groppa S (2017) Effects of DBS in parkinsonian patients depend on the structural integrity of frontal cortex. Sci Rep 7:43571.

>> Link to PubMed

Droby A, Yuen KS, Muthuraman M, Reitz SC, Fleischer V, Klein J, Gracien RM, Ziemann U, Deichmann R, Zipp F, Groppa S (2015) Changes in brain functional connectivity patterns are driven by an individual lesion in MS: a resting-state fMRI study. Brain Imaging Behav 10(4):1117-1126.

>> Link to PubMed

Groppa S, Herzog J, Falk D, Riedel C, Deuschl G, Volkmann J (2014) Physiological and anatomical decomposition of subthalamic neurostimulation effects in essential tremor. Brain 137:109-21.

>> Link to PubMed

Groppa S, Muthuraman M, Otto B, Deuschl G, Siebner HR, Raethjen J (2013) Subcortical substrates of TMS induced modulation of the cortico-cortical connectivity. Brain Stimul 6:138-46.

>> Link to PubMed

Groppa S, Werner-Petroll N, Munchau A, Deuschl G, Rushworth MF, Siebner HR (2012) A novel dual-site transcranial magnetic stimulation paradigm to probe fast facilitatory inputs from ipsilateral dorsal premotor cortex to primary motor cortex. Neuroimage 62:500-9.

>> Link to PubMed

Awards, Grants and Honor


Most Cited manuscript of the "Clinical Neurophysiology", Elsevier, "A practical guide to transcranial magnetic stimulation diagnostic: Report of an IFCN committee"


Poster Award, DGKN, Cologne


Most read manuscripts of the "Clinical Neurophysiology", Thieme Verlag, "Funktionsdiagnostik der kortikomotorischen Bahnen mit der transkraniellen Magnetstimulation: eine Einführung“


Grant of the Movement Disorders Society

2004 – 2007

Scholarship of the Friedrich Ebert Foundation Bonn

2000 – 2001

Scholarship of the DESITIN GmbH Foundation, Hamburg

Since 2009

Founding member of Romanian Society for Neurophysiology


Since 2009

Founding member of Romanian Society for Neurophysiology


Fellow of the European Federation of Neurological Societies

Since 2008

Member of German Society of Neurology (DGN)

Since 2007

Member of Human Brain Mapping Society